Dr. Grace Lu-Yao is an internationally recognized leader in geriatric oncology, whose pioneering research has significantly advanced the understanding of how comorbidity influences cancer treatment outcomes in older adults. Her work aims to facilitate individualized, patient-centered approaches to cancer care by integrating aging-related vulnerabilities into treatment decision-making. She is the inaugural Associate Director of Population Science at the Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, where she has led a multidisciplinary research team to evaluate treatment benefits and risks in older adults with cancer. She also co-founded the Geriatric Oncology Research Working Group at the Sidney Kimmel Comprehensive Cancer Center to foster interdisciplinary collaboration and accelerate research to improve outcomes for older adults with cancer. Her contributions have informed evidence-based prostate cancer management guidelines, promoting the incorporation of frailty, comorbidity, and life expectancy into clinical practice. In recognition of her impactful contributions to geriatric oncology, Dr. Lu-Yao received the 2018 International Society of Geriatric Oncology (SIOG) Allied Health and Nursing Investigator Award. Through her scientific leadership and collaborative initiatives, she continues to advance the field of geriatric oncology and improve cancer care for older adults worldwide.