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Oral chemotherapy treatment in the elderly with solid tumours Task Force

SIOG has identified that there is a need to make recommendations concerning oral chemotherapy treatment for older patients with cancer.

All cancer patients benefit from the use of active oral chemotherapy, which avoids the often needed venous access devices and allows treatment near to their home, under care by their usual physician in collaboration with appropriate experts. Presently two oral agents are widely used in the treatment of solid tumours, and are capecitabine and vinorelbine. Oral vinorelbine is not available in the USA and any other countries. The oral regimen combination of cyclophosphamide and methotrexate is also used in breast cancer.

To review the available evidence showing that oral chemotherapy is beneficial in older patients.

Task Force Members

Matti Aapro, Switzerland
Laura Biganzoli, Italy
Elisabeth Quoix, France
Demetris Papamichael, Cyprus

Christine Walko,USA
Stuart Lichtman, USA
Jean-Pierre Michel, Switzerland



Oral single-agent chemotherapy in older patients with solid tumours: A position paper from the International Society of Geriatric Oncology (SIOG).  L. Biganzoli, S. Lichtman , J.-P. Michel , D. Papamichael , E. Quoix , C. Walko , M. Aapro. European Journal of Cancer 

This project was supported by unrestricted grants from Roche and Pierre Fabre.